Cold Medicine

So, after falling asleep when I got home from work and wasting yet another day, I went on a quest to find the ultimate cold medicine, and no john, I didn’t buy the humidifier.

If this isn’t a great case of OCD, I don’t know what is. I looked at the ingredients in every cold product I could find, and found that all of them contained the same nasal decongestants.

Everything with the exception of Alka-Seltzers line of products contain:
Pseudoephedrine hydrochloride, some had Pseudoephedrine Sulfate, which apparantly is the same, except for it molecular weight (the sulfate version is heavier).
How Supplied: Pseudoephedrine hydrochloride: Liquid: 7.5 mg/0.8 mL, 30 mg/5 mL; Syrup: 15 mg/5 mL, 30 mg/5 mL; Tablet: 30 mg, 60 mg; Tablet, extended release: 120 mg, 240 mg. Pseudoephedrine sulfate: Tablet: 60 mg
What it does: Produces direct stimulation of both alpha-(pronounced) and beta-adrenergic receptors, as well as indirect stimulation through release of norepinephrine from storage sites. Results in decongestant effect on the nasal mucosa. Systemic administration eliminates possible damage to the nasal mucosa. Onset: 15-30 min. Time to peak effect: 30-60 min. Duration: 3-4 hr. Extended-release: duration, 8-12 hr. Urinary excretion slowed by alkalinization, causing reabsorption of drug.

Alka-Seltzer contained:
Phenylephrine hydrochloride (5mg)
How Supplied: Injection: 10 mg/mL; Liquid: 5 mg/5 mL; Nasal Solution: 0.125%, 0.25%, 0.5%, 1%; Ophthalmic Solution: 0.12%, 2.5%, 10%; Nasal Spray: 0.25%, 0.5%, 1%
What it does: Stimulates alpha-adrenergic receptors, producing pronounced vasoconstriction and hence an increase in both SBP and DBP; reflex bradycardia results from increased vagal activity. Also acts on alpha receptors producing vasoconstriction in the skin, mucous membranes, and the mucosa as well as mydriasis by contracting the dilator muscle of the pupil. Resembles epinephrine, but it has more prolonged action and few cardiac effects. IV: Onset, immediate; duration, 15-20 min. IM, SC: Onset, 10-15 min; duration: 0.5-2 hr for IM and 50-60 min for SC. Nasal decongestion (topical): Onset: 15-20 min; duration, 30 min-4 hr. Ophthalmic: Time to peak effect for mydriasis, 15-60 min for 2.5% solution and 10-90 min for 10% solution. Duration: 0.5-1.5 hr for 0.12%, 3 hr for 2.5%, and 5-7 hr with 10% (when used for mydriasis). Excreted in urine.

It’s kind of funny that you have all these choices of cold products, but they are all the same damn thing! I think the Alka-Seltzer stuff is junk, and instead I need to find myself the 60mg (or 240mg extended release) version of the Pseudoephedrine Hydrochloride.

After extensive research, these are the winners:
CVS Decongestant Antihistamine (generic version of sudafed) $3.99
SUDAFED 24 Hour Tablets (The extended release version with 240mg) $7,79

Oddly enough, the CVS brand comes with 24 pills, and the Sudafed extended release kind comes with 10 pills for twice the price. (16cents/pill versus 77 cents/pull) so really, taking the CVS brand twice every 12 hours is still a ton cheaper than taking 1 extended release 12 hour sudafed.

As Ash would put it, even though Acadia already quoted it once, I leave you with these parting words:
“Shop smart, Shop S-mart”

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